DelveInsight’s, “Eosinophilic Esophagitis Pipeline Insight 2023” report provides comprehensive insights about 18+ companies and 20+ pipeline drugs in the Eosinophilic Esophagitis pipeline landscape. It covers the Eosinophilic Esophagitis pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Eosinophilic Esophagitis pipeline therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Key Takeaways from the Eosinophilic Esophagitis Pipeline Report
- DelveInsight’s Eosinophilic Esophagitis pipeline report depicts a robust space with 18+ active players working to develop 20+ pipeline therapies for Eosinophilic Esophagitis treatment.
- The leading companies working in the Eosinophilic Esophagitis Market include AstraZeneca, Bristol Myers Squibb, Ellodi Pharmaceuticals, Allakos, EsoCap AG, Arena Pharmaceuticals, GlaxoSmithKline, Landos Biopharma, Calypso Biotech, Takeda, Dr Falk Pharma, DBV Technologies, Revolo Biotherapeutics, EsoCap, Aqilion, Serpin Pharma, and others.
- Promising Eosinophilic Esophagitis Pipeline Therapies in the various stages of development include Tezepelumab, Etrasimod, Reslizumab, Dupilumab, ESO-101, NDX-3315, and others.
- September 2023: Ellodi Pharmaceuticals LP announced a study of phase 3 clinical trials for APT-1011. This is a 24-week randomized, double-blind, placebo-controlled induction study of APT-1011 in adults (≥18 years old) with eosinophilic esophagitis (EoE) followed by a single-arm, open-label extension. This study will evaluate the efficacy and safety of APT-1011 3 mg administered HS (hora somni, at bedtime) for the induction of response to treatment (symptomatic and histologic) over 24 weeks. The open-label extension will continue to evaluate long-term safety in subjects who consent to continue on open-label treatment with APT-1011.
- September 2023: Celgene announced a study of phase 3 clinical trials for CC-93538. This study is an open-label, uncontrolled study design to evaluate the long-term safety and tolerability of treatment with CC-93538. The study will enroll participants who participated in the CC-93538-EE-001 or CC-93538-DDI-001 studies.
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In the Eosinophilic Esophagitis pipeline report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, licensing, mergers and acquisition, funding, designations and other product related details. Eosinophilic Esophagitis (EoE) occurs as a result of an immunogenic reaction to various antigens which are commonly found in food and air. There is a strong genetic component involved in the pathogenesis of EoE and a high concordance reported for EoE among family members. Study reported that the gene responsible for EoE was TSLP which is located in the 5q22 region of male X chromosome. TSLP stimulates Th2 cells and induces eotaxin-3.
Eosinophilic Esophagitis Overview
Eosinophilic esophagitis (EoE) is a chronic disorder of the digestive system in which large numbers of a particular type of white blood cell called eosinophils are present in the esophagus. The esophagus is the tube that carries food from the mouth to the stomach. Eosinophils can be found in the esophagus in response to various stimuli or antigen.
Find out more about Eosinophilic Esophagitis Therapeutics Assessment @ Eosinophilic Esophagitis Preclinical and Discovery Stage Products
Eosinophilic Esophagitis Emerging Drugs Profile
- APT-1011: Ellodi Pharmaceuticals.
Eosinophilic Esophagitis Pipeline Therapeutics Assessment
There are approx. 18+ key companies which are developing the Eosinophilic Esophagitis therapies. The Eosinophilic Esophagitis companies which have their Eosinophilic Esophagitis drug candidates in the most advanced stage, i.e. Phase III include, Ellodi Pharmaceuticals.
Learn more about the emerging Eosinophilic Esophagitis Pipeline Therapies @ Eosinophilic Esophagitis Clinical Trials Assessment
Scope of the Eosinophilic Esophagitis Pipeline Report
- Coverage- Global
- Eosinophilic Esophagitis Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
- Eosinophilic Esophagitis Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
- Eosinophilic Esophagitis Companies- AstraZeneca, Bristol Myers Squibb, Ellodi Pharmaceuticals, Allakos, EsoCap AG, Arena Pharmaceuticals, GlaxoSmithKline, Landos Biopharma, Calypso Biotech, Takeda, Dr Falk Pharma, DBV Technologies, Revolo Biotherapeutics, EsoCap, Aqilion, Serpin Pharma, and others.
- Eosinophilic Esophagitis Pipeline Therapies- Tezepelumab, Etrasimod, Reslizumab, Dupilumab, ESO-101, NDX-3315, and others.
Dive deep into rich insights for new drugs for Eosinophilic Esophagitis Treatment, Visit @ Eosinophilic Esophagitis Market Drivers and Barriers, and Future Perspective
Table of Content
- Introduction
- Executive Summary
- Eosinophilic Esophagitis: Overview
- Pipeline Therapeutics
- Therapeutic Assessment
- Eosinophilic Esophagitis – DelveInsight’s Analytical Perspective
- Late Stage Products (Phase III)
- Benralizumab: AstraZeneca
- Drug profiles in the detailed report…..
- Mid Stage Products (Phase II)
- IRL201104: Revolo Biotherapeutics
- Drug profiles in the detailed report…..
- Mid Stage Products (Phase II)
- Mometasone: EsoCap
- Drug profiles in the detailed report…..
- Early Stage Products (Phase I)
- AQ280: Aqilion
- Drug profiles in the detailed report…..
- Preclinical and Discovery Stage Products
- SP 16: Serpin Pharma
- Drug profiles in the detailed report…..
- Inactive Products
- Eosinophilic Esophagitis Key Companies
- Eosinophilic Esophagitis Key Products
- Eosinophilic Esophagitis- Unmet Needs
- Eosinophilic Esophagitis- Market Drivers and Barriers
- Eosinophilic Esophagitis- Future Perspectives and Conclusion
- Eosinophilic Esophagitis Analyst Views
- Eosinophilic Esophagitis Key Companies
- Appendix
For further information on the Eosinophilic Esophagitis Pipeline therapeutics, reach out to Eosinophilic Esophagitis Unmet Needs and Analyst Views
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