Tuesday, February 17, 2026

Friedreich's Ataxia Clinical Trial Pipeline Expands as 10+ Companies Progress 10+ Novel Therapies Toward Market Entry, Finds DelveInsight | PTC Therapeutics, Retrotope, Reata Pharmaceuticals, Minoryx

Friedreich's Ataxia Clinical Trial Pipeline Expands as 10+ Companies Progress 10+ Novel Therapies Toward Market Entry, Finds DelveInsight | PTC Therapeutics, Retrotope, Reata Pharmaceuticals, Minoryx
Friedreich's Ataxia – Pipeline Insight, 2026
DelveInsight's "Friedreich's Ataxia – Pipeline Insight, 2026" report provides comprehensive insights about 10+ companies including PTC Therapeutics, Retrotope, Reata Pharmaceuticals, Minoryx Therapeutics, Larimar Therapeutics, LEXEO Therapeutics, Exicure, StrideBio, Voyager Therapeutics, Lacerta Therapeutics and others, developing 10+ pipeline drugs in the Friedreich's Ataxia pipeline landscape.

DelveInsight’s “Friedreich’s Ataxia – Pipeline Insight, 2026” report provides comprehensive insights about 10+ companies developing 10+ pipeline drugs in the Friedreich’s Ataxia pipeline landscape. It covers the Friedreich’s Ataxia pipeline drug profiles, including clinical and nonclinical stage products, along with therapeutics assessment by product type, stage, route of administration, and molecule type, and further highlights inactive pipeline products in this space.

Explore the latest breakthroughs in the Friedreich’s Ataxia treatment landscape. Learn more about the evolving Friedreich’s Ataxia pipeline today @ https://www.delveinsight.com/report-store/friedreich-ataxia-pipeline-insight?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=xpr

Key Takeaways from the Friedreich’s Ataxia Pipeline Report

  • In October 2025, Lexeo Therapeutics released positive interim data for LX2006 from SUNRISE-FA Phase 1/2 and Weill Cornell Phase 1A trials, planning pivotal study in H1 2026.

  • In July 2025, the FDA granted Breakthrough Therapy designation to Lexeo Therapeutics' LX2006 based on cardiac and neurologic data.

  • The leading Friedreich’s Ataxia companies include PTC Therapeutics, Retrotope, Reata Pharmaceuticals, Minoryx Therapeutics, Larimar Therapeutics, LEXEO Therapeutics, Exicure, StrideBio, Voyager Therapeutics, Lacerta Therapeutics and others.

  • Promising Friedreich’s Ataxia therapies include EPI-743, RT001, Idebenone, Lu AA24493, MIB-626, DT-216P2, CTI-1601, MIN-102 and others.

Download for updates and the latest revolution in Friedreich’s Ataxia care @ Friedreich’s Ataxia Clinical Trials Assessment

Friedreich’s Ataxia Emerging Drugs Profile

  • RT 001: Retrotope

Curently in Phase III stage of development for Friedreich's ataxia, RT001 is a clinical-stage isotopically stabilized, synthetic linoleic acid (LA) discovered and developed with Retrotope’s novel platform technology. This platform is designed to combat the oxidative stress and cellular degeneration that arises from lipid peroxidation (LPO).

  • Leriglitazone: Minoryx Therapeutics

Currently in phase II stage of development, Leriglitazone (MIN-102) is a novel, orally bioavailable and selective PPAR gamma agonist with a potential best-in-class profile indicated for CNS diseases. This is being developed by Minoryx Therapeutics. It is one of the several metabolites of pioglitazone and has a demonstrated sufficient brain penetration and favorable safety profile in humans, allowing PPAR gamma engagement in the CNS above the level that can be safely achieved with pioglitazone and other glitazones.

For more information on the Friedreich’s Ataxia Emerging Drugs Profile, download DelveInsight’s comprehensive Friedreich’s Ataxia Pipeline Insight report.

The Friedreich’s Ataxia Pipeline Report Provides

  • Detailed insights about companies developing therapies for Friedreich’s Ataxia, with aggregate therapies developed by each company.

  • Different therapeutic candidates, segmented into early-stage, mid-stage, and late-stage of development for Friedreich’s Ataxia treatment.

  • Friedreich’s Ataxia companies that are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.

  • Friedreich’s Ataxia drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.

  • Detailed analysis of collaborations (company–company and company–academia), licensing agreements, and financing details for future advancement of the Friedreich’s Ataxia market.

Learn more about Friedreich’s Ataxia Drugs opportunities in our comprehensive Friedreich’s Ataxia pipeline report @ Friedreich’s Ataxia Unmet Needs

Friedreich’s Ataxia Companies

There are 10+ key companies, such as PTC Therapeutics, Retrotope, Reata Pharmaceuticals, Minoryx Therapeutics, Larimar Therapeutics, LEXEO Therapeutics, Exicure, StrideBio, Voyager Therapeutics, Lacerta Therapeutics and others, developing therapies for Friedreich’s Ataxia.

DelveInsight’s Friedreich’s Ataxia pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as:

  • Infusion

  • Intradermal

  • Intramuscular

  • Intranasal

  • Oral

  • Parenteral

  • Subcutaneous

  • Topical

  • Molecule Type

Friedreich’s Ataxia products have been categorized under various Molecule types such as:

  • Vaccines

  • Monoclonal Antibody

  • Peptides

  • Polymer

  • Small molecule

  • Product Type

Discover the latest advancements in Friedreich’s Ataxia treatment by visiting our website. Stay informed @ Friedreich’s Ataxia Market Drivers and Barriers, and Future Perspectives.

Scope of the Friedreich’s Ataxia Pipeline Report

  • Coverage: Global​

  • Friedreich’s Ataxia companies: PTC Therapeutics, Retrotope, Reata Pharmaceuticals, Minoryx Therapeutics, Larimar Therapeutics, LEXEO Therapeutics, Exicure, StrideBio, Voyager Therapeutics, Lacerta Therapeutics and others

  • Friedreich’s Ataxia Therapies: EPI-743, RT001, Idebenone, Lu AA24493, MIB-626, DT-216P2, CTI-1601, MIN-102 and others.

  • Friedreich’s Ataxia Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination​

  • Friedreich’s Ataxia Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III

Table of Contents

  1. Introduction

  2. Executive Summary

  3. Friedreich’s Ataxia: Overview

  4. Pipeline Therapeutics

  5. Therapeutic Assessment

  6. Friedreich’s Ataxia – DelveInsight’s Analytical Perspective

  7. Late Stage Products (Phase III)

  8. Mid Stage Products (Phase II)

  9. Early Stage Products (Phase I)

  10. Preclinical and Discovery Stage Products

  11. Inactive Products

  12. Friedreich’s Ataxia Key Companies

  13. Friedreich’s Ataxia Key Products

  14. Friedreich’s Ataxia Unmet Needs

  15. Friedreich’s Ataxia Market Drivers and Barriers

  16. Friedreich’s Ataxia Future Perspectives and Conclusion

  17. Friedreich’s Ataxia Analyst Views

  18. Appendix

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