DelveInsight’s, “AL Amyloidosis Pipeline Insight 2024” report provides comprehensive insights about 10+ companies and 10+ pipeline drugs in AL Amyloidosis pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Discover the latest drugs and treatment options in the AL Amyloidosis Pipeline. Dive into DelveInsight's comprehensive report today! @ AL Amyloidosis Pipeline Outlook
Key Takeaways from the AL Amyloidosis Pipeline Report
- In October 2024:- Alexion Pharmaceuticals Inc.- A Phase 3, Double-Blind, Multicenter Study to Evaluate the Efficacy and Safety of CAEL-101 and Plasma Cell Dyscrasia Treatment Versus Placebo and Plasma Cell Dyscrasia Treatment in Plasma Cell Dyscrasia Treatment Naïve Patients With Mayo Stage IIIa AL Amyloidosis.
- In October 2024:- AbbVie- Immunoglobulin light chain (AL) amyloidosis is the most common form of systemic amyloidosis. AL amyloidosis has many root causes and is characterized by the overproduction of AL that are secreted by clonal bone marrow plasma cells. This is a study to determine adverse events and change in disease activity in adult participants with AL amyloidosis treated with ABBV-383.
- DelveInsight’s AL Amyloidosis pipeline report depicts a robust space with 10+ active players working to develop 10+ pipeline therapies for AL Amyloidosis treatment.
- The leading AL Amyloidosis Companies such as Caelum Biosciences, Nexcella, Inc., HaemaLogiX Ltd., Prothena, ZENTALIS PHARMACEUTICALS, Sorrento Therapeutics, Inc., and others.
- Promising AL Amyloidosis Therapies such as Belantamab mafodotin, CAEL-101, Daratumumab SC, Pomalidomide, Dexamethasone, and others.
Stay ahead with the most recent pipeline outlook for AL Amyloidosis. Get insights into clinical trials, emerging therapies, and leading companies with DelveInsight @ AL Amyloidosis Treatment Drugs
AL Amyloidosis Emerging Drugs
- CAEL-101: Caelum Biosciences
CAEL-101 is a fibril-reactive monoclonal antibody (mAb) that is currently in Phase III clinical development for the treatment of patients with amyloid light chain (“AL”) amyloidosis. The Cardiac Amyloid Reaching for Extended Survival (CARES) clinical program includes two parallel Phase III studies – one in patients with Mayo stage IIIa disease and one in patients with Mayo stage IIIb disease – and will collectively enroll approximately 370 patients globally. The primary objective of the clinical program is to assess overall survival. CAEL-101 has received Orphan Drug Designation from both the US Food and Drug Administration and European Medicine Agency as a therapy for patients with AL amyloidosis.
- NXC-201: Nexcella, Inc.
NXC-201 (formerly HBI0101) is a BCMA-targeted investigational chimeric antigen receptor T (CAR-T) cell therapy that is being studied in a comprehensive clinical development program for the treatment of patients with relapsed or refractory multiple myeloma and AL amyloidosis. The design consists of a structurally differentiated CAR-T, with the proprietary BCMA-targeting CAR, which has demonstrated reduced toxicity in NEXICART-1, supporting investigating NXC-201 as an outpatient therapy. It is currently in Phase I NEXICART-1 study of its novel, autologous, BCMA-targeted chimeric antigen receptor T (CAR-T) cell therapy for the treatment of patients with relapsed or refractory multiple myeloma and light chain amyloidosis (AL).
Explore groundbreaking therapies and clinical trials in the AL Amyloidosis Pipeline. Access DelveInsight's detailed report now! @ New AL Amyloidosis Drugs
AL Amyloidosis pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration
- Intra-articular
- Intraocular
- Intrathecal
- Intravenous
- Ophthalmic
- Oral
- Parenteral
- Subcutaneous
- Topical
- Transdermal
AL Amyloidosis Products have been categorized under various Molecule types such as
- Oligonucleotide
- Peptide
- Small molecule
Unveil the future of AL Amyloidosis Treatment. Learn about new drugs, pipeline developments, and key companies with DelveInsight's expert analysis @ AL Amyloidosis Market Drivers and Barriers
Scope of the AL Amyloidosis Pipeline Report
- Coverage- Global
- AL Amyloidosis Companies- Caelum Biosciences, Nexcella, Inc., HaemaLogiX Ltd., Prothena, ZENTALIS PHARMACEUTICALS, Sorrento Therapeutics, Inc., and others.
- AL Amyloidosis Therapies- Belantamab mafodotin, CAEL-101, Daratumumab SC, Pomalidomide, Dexamethasone, and others.
- AL Amyloidosis Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
- AL Amyloidosis Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
Get the latest on AL Amyloidosis Therapies and clinical trials. Download DelveInsight's in-depth pipeline report today! @ AL Amyloidosis Companies, Key Products and Unmet Needs
Table of Content
- Introduction
- Executive Summary
- AL Amyloidosis: Overview
- Pipeline Therapeutics
- Therapeutic Assessment
- AL Amyloidosis– DelveInsight’s Analytical Perspective
- Late Stage Products (Phase III)
- CAEL-101: Caelum Biosciences
- Drug profiles in the detailed report…..
- Mid Stage Products (Phase II)
- Drug Name: Company Name
- Drug profiles in the detailed report…..
- Early Stage Products (Phase I)
- NXC-201: Nexcella, Inc.
- Drug profiles in the detailed report…..
- Preclinical and Discovery Stage Products
- LambdaMab 10B3 & 7F11: HaemaLogiX Ltd.
- Drug profiles in the detailed report…..
- Inactive Products
- AL Amyloidosis Key Companies
- AL Amyloidosis Key Products
- AL Amyloidosis- Unmet Needs
- AL Amyloidosis- Market Drivers and Barriers
- AL Amyloidosis- Future Perspectives and Conclusion
- AL Amyloidosis Analyst Views
- AL Amyloidosis Key Companies
- Appendix
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