DelveInsight has launched a new report on "Fabry disease-Market Insights, Epidemiology, and Market Forecast-2030”.
DelveInsight’s “Fabry disease–Market Insights, Epidemiology, and Market Forecast-2030” report delivers an in-depth understanding of the Fabry disease, historical and forecasted epidemiology as well as the Fabry disease market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.
Some of the key facts of the Report:
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According to National Organization for Rare Diseases (NORD), It is estimated that type 1 classic Fabry disease affects approximately one in 40,000 males. The type 2 later-onset phenotype is more frequent than the type 1 phenotype by 3-10 fold, and in some populations may occur as frequently as about 1 in 1,500 to 4,000 males.
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US estimate for Fabry disease described in the National Institutes of Health Genetics Home Reference states Fabry disease affects an estimated 1 in 40,000 to 60,000 males.
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In a study by Colon et al, 2017 newborn screening for Fabry disease performed on the Spanish population revealed a prevalence of genetic alterations in GLA of 0.1% in males (0.013% with classic Fabry disease)
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In a study by Doheny et al, 2018 prevalence estimates: among 36820 (23954M and 12866F) haemodialysis screenees, 0.21% males and 0.15% females; among 3074 (2031M and 1043F) renal transplant screenees, 0.25% males and no females; among 5491 (4054M and 1437F) cardiac screenees, 0.94% males and 0.90% females; and among 5978 (3904M and 2074F) stroke screenees, 0.13% males and 0.14% females. Among male and female screenees with pathogenic mutations, the type 1 Classic phenotype was predominant (~60%), except more male cardiac patients (75%) had type 2 Later-Onset phenotype.
Key benefits of the report:
1.The Fabry disease market report covers a descriptive overview and comprehensive insight of the Fabry disease epidemiology and Fabry disease market in the 7MM (the United States, EU5 (Germany, Spain, France, Italy, UK) & Japan.)
2.The Fabry disease market report provides insights into the current and emerging therapies.
3.Fabry disease market report provides a global historical and forecasted market covering drug outreach in 7MM.
4.The Fabry disease market report offers an edge that will help in developing business strategies by understanding trends shaping and driving the Fabry disease market.
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Fabry disease: Overview
Fabry disease (FD) is a devastating, progressive, inherited condition caused by lysosomal dysfunction linked to chromosome X and mutations in the GLA gene located in chromosome Xq22.1 which encodes the alpha-galactosidase A (AGA) enzyme.
It is a multi-systemic and life-threatening condition that is one of the most common lysosomal storage diseases after the Gaucher Disease. It is characterized by specific neurological, cutaneous, renal, cardiovascular, cochleovestibular, and cerebrovascular manifestations. The symptoms include Chronic pain, usually a burning or tingling sensation in the hands and feet. The pain sometimes briefly becomes more intense, requiring medication to bring it down to manageable levels.
The key players involved in the Fabry disease market:
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Safoni Genzyme
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Idorsia Pharmaceuticals
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Protalix Biotherapeutics
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Sangamo Therapeutics
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4D MolecularTherapeutics
The launch of the emerging therapies is expected to significantly impact the Fabry disease treatment scenario in the upcoming years:-
Drug covered
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Venglustat
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Lucerastat
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PRX- 102
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ST 920
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4D-310
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Table of Contents
1. Report Introduction
2. Executive Summary
3. SWOT analysis
4. Fabry disease Patient Share (%) Overview at a Glance
5. Fabry disease Market Overview at a Glance
6. Fabry disease Disease Background and Overview
7. Fabry disease Epidemiology and Patient Population
8. Country-Specific Patient Population of Fabry disease
9. Fabry disease Current Treatment and Medical Practices
10. Unmet Needs
11. Fabry disease Emerging Therapies
12. Fabry disease Market Outlook
13. Country-Wise Fabry disease Market Analysis (2017–2030)
14. Market Access and Reimbursement of Therapies
15. Market drivers
16. Market barriers
17. Appendix
18. Fabry disease Report Methodology
19. DelveInsight Capabilities
20. Disclaimer
21. About DelveInsight
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