“CDK12 Inhibitor Pipeline Insight, 2025" report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the CDK12 Inhibitor Market.
The CDK12 Inhibitor Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.
Some of the key takeaways from the CDK12 Inhibitor Pipeline Report:
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Companies across the globe are diligently working toward developing novel CDK12 Inhibitor treatment therapies with a considerable amount of success over the years.
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CDK12 Inhibitor companies working in the treatment market are Insilico Medicine, Chordia Therapeutics, Carrick Therapeutics, and others, are developing therapies for the CDK12 Inhibitor treatment
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Emerging CDK12 Inhibitor therapies in the different phases of clinical trials are- Cyclin-dependent kinase 12 (CDK12) Inhibitor CTX 439, CT7439, and others are expected to have a significant impact on the CDK12 Inhibitor market in the coming years.
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In March 2025, Insilico Medicine, a biotechnology firm utilizing generative artificial intelligence (AI), announced a major advancement in cancer treatment. Their recent study, featured in the *Journal of Medicinal Chemistry*, highlights the discovery of a new class of orally available covalent CDK12/13 dual inhibitors, developed to target refractory and treatment-resistant cancers
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In September 2024, Carrick Therapeutics Inc., a biopharmaceutical company focused on oncology, announced the dosing of the first patient in its Phase I clinical trial of CT7439. This novel therapy acts as both a cyclin-dependent kinase 12/13 (CDK12/13) inhibitor and a Cyclin-K gluedegrader. CDK12/13 plays a key role in several cancer types by regulating transcription elongation, RNA splicing, and RNA processing. Inhibiting CDK12/13 particularly affects the expression of DNA damage response genes. The trial is enrolling patients with advanced solid tumors, including ovarian cancer, breast cancer, and Ewing's Sarcoma.
CDK12 Inhibitor Overview
A CDK12 inhibitor is a type of targeted therapy designed to block the activity of Cyclin-Dependent Kinase 12 (CDK12), an enzyme involved in regulating gene transcription, DNA repair, and cell cycle progression. CDK12 plays a critical role in maintaining the expression of genes essential for DNA damage repair, especially through the homologous recombination (HR) pathway. Inhibiting CDK12 can impair cancer cells' ability to repair DNA, making them more sensitive to DNA-damaging treatments like chemotherapy and PARP inhibitors. CDK12 inhibitors are being explored as potential cancer therapies, particularly in tumors with CDK12 mutations or HR deficiencies.
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Emerging CDK12 Inhibitor Drugs Under Different Phases of Clinical Development Include:
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Cyclin-dependent kinase 12 (CDK12) Inhibitor: Insilico Medicine
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CTX 439: Chordia Therapeutics
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CT7439: Carrick Therapeutics
CDK12 Inhibitor Route of Administration
CDK12 Inhibitor pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as
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Oral
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Parenteral
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Intravenous
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Subcutaneous
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Topical
CDK12 Inhibitor Molecule Type
CDK12 Inhibitor Products have been categorized under various Molecule types, such as
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Monoclonal Antibody
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Peptides
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Polymer
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Small molecule
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Gene therapy
CDK12 Inhibitor Pipeline Therapeutics Assessment
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CDK12 Inhibitor Assessment by Product Type
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CDK12 Inhibitor By Stage and Product Type
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CDK12 Inhibitor Assessment by Route of Administration
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CDK12 Inhibitor By Stage and Route of Administration
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CDK12 Inhibitor Assessment by Molecule Type
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CDK12 Inhibitor by Stage and Molecule Type
DelveInsight's CDK12 Inhibitor Report covers around 3+ products under different phases of clinical development like
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Late-stage products (Phase III)
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Mid-stage products (Phase II)
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Early-stage product (Phase I)
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Pre-clinical and Discovery stage candidates
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Discontinued & Inactive candidates
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Route of Administration
Further CDK12 Inhibitor product details are provided in the report. Download the CDK12 Inhibitor pipeline report to learn more about the emerging CDK12 Inhibitor therapies
Some of the key companies in the CDK12 Inhibitor Therapeutics Market include:
Key companies developing therapies for CDK12 Inhibitors are - Carrick Therapeutics, OnKure Therapeutics, and others.
CDK12 Inhibitor Pipeline Analysis:
The CDK12 Inhibitor pipeline report provides insights into
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The report provides detailed insights about companies that are developing therapies for the treatment of CDK12 Inhibitor with aggregate therapies developed by each company for the same.
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It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for CDK12 Inhibitor Treatment.
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CDK12 Inhibitor key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
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CDK12 Inhibitor Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
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Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the CDK12 Inhibitor market.
The report is built using data and information traced from the researcher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.
Download Sample PDF Report to know more about CDK12 Inhibitor drugs and therapies
CDK12 Inhibitor Pipeline Market Drivers
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The increasing prevalence of cancer drives demand for innovative and targeted therapies, positioning CDK12 inhibitors as a promising treatment option for transcription factor dependent and hard-to-treat cancers, are some of the important factors that are fueling the CDK12 Inhibitor Market.
CDK12 Inhibitor Pipeline Market Barriers
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However, The high cost associated with CDK12 inhibitor treatment limits patient access and places a financial burden on healthcare systems, making it a significant market barrier to widespread adoption and other factors are creating obstacles in the CDK12 Inhibitor Market growth.
Scope of CDK12 Inhibitor Pipeline Drug Insight
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Coverage: Global
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Key CDK12 Inhibitor Companies: Insilico Medicine, Chordia Therapeutics, Carrick Therapeutics, and others
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Key CDK12 Inhibitor Therapies: Cyclin-dependent kinase 12 (CDK12) Inhibitor CTX 439, CT7439, and others
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CDK12 Inhibitor Therapeutic Assessment: CDK12 Inhibitor current marketed and CDK12 Inhibitor emerging therapies
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CDK12 Inhibitor Market Dynamics: CDK12 Inhibitor market drivers and CDK12 Inhibitor market barriers
Request for Sample PDF Report for CDK12 Inhibitor Pipeline Assessment and clinical trials
Table of Contents
1. CDK12 Inhibitor Report Introduction
2. CDK12 Inhibitor Executive Summary
3. CDK12 Inhibitor Overview
4. CDK12 Inhibitor- Analytical Perspective In-depth Commercial Assessment
5. CDK12 Inhibitor Pipeline Therapeutics
6. CDK12 Inhibitor Late Stage Products (Phase II/III)
7. CDK12 Inhibitor Mid Stage Products (Phase II)
8. CDK12 Inhibitor Early Stage Products (Phase I)
9. CDK12 Inhibitor Preclinical Stage Products
10. CDK12 Inhibitor Therapeutics Assessment
11. CDK12 Inhibitor Inactive Products
12. Company-University Collaborations (Licensing/Partnering) Analysis
13. CDK12 Inhibitor Key Companies
14. CDK12 Inhibitor Key Products
15. CDK12 Inhibitor Unmet Needs
16 . CDK12 Inhibitor Market Drivers and Barriers
17. CDK12 Inhibitor Future Perspectives and Conclusion
18. CDK12 Inhibitor Analyst Views
19. Appendix
20. About DelveInsight
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About DelveInsight
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