Thursday, February 20, 2025

HPV+ Recurrent/Metastatic Head and Neck Cancer Clinical Trials and Studies: EMA, PDMA, FDA Approvals, Mechanism of Action, ROA, NDA, IND, and Companies

HPV+ Recurrent/Metastatic Head and Neck Cancer Clinical Trials and Studies: EMA, PDMA, FDA Approvals, Mechanism of Action, ROA, NDA, IND, and Companies

DelveInsight’s, “HPV+ Recurrent/Metastatic Head and Neck Cancer Pipeline Insight” report provides comprehensive insights about 5+ companies and 5+ pipeline drugs in the HPV+ Recurrent/Metastatic Head and Neck Cancer pipeline landscape. It covers the HPV+ Recurrent/Metastatic Head and Neck Cancer pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Stay ahead with the latest insights! Download DelveInsight’s comprehensive HPV+ Recurrent/Metastatic Head and Neck Cancer Pipeline Report to explore emerging therapies, key HPV+ Recurrent/Metastatic Head and Neck Cancer Companies, and future HPV+ Recurrent/Metastatic Head and Neck Cancer treatment landscapes @ HPV+ Recurrent/Metastatic Head and Neck Cancer Pipeline Outlook Report

Key Takeaways from the HPV+ Recurrent/Metastatic Head and Neck Cancer Pipeline Report

  • In January 2025:- BioNTech SE:- An open-label, controlled, multi-site, interventional, 2-arm, Phase II trial of BNT113 in combination with pembrolizumab vs pembrolizumab monotherapy as first line treatment in patients with unresectable recurrent or metastatic HPV16+ HNSCC expressing programmed cell death ligand -1 (PD-L1) with combined positive score (CPS) ≥1.
  • DelveInsight’s HPV+ Recurrent/Metastatic Head and Neck Cancer pipeline report depicts a robust space with 5+ active players working to develop 5+ pipeline therapies for HPV+ Recurrent/Metastatic Head and Neck Cancer treatment.
  • The leading HPV+ Recurrent/Metastatic Head and Neck Cancer Companies such as BioNTech, Cue Biopharma, Hookipa Pharma, and others.
  • Promising HPV+ Recurrent/Metastatic Head and Neck Cancer Pipeline Therapies such as MEDI0457, Durvalumab, CUE-101, Keytruda, BNT113, Pembrolizumab, palbociclib, Cetuximab, and others.

Discover how the HPV+ Recurrent/Metastatic Head and Neck Cancer treatment paradigm is evolving. Access DelveInsight’s in-depth HPV+ Recurrent/Metastatic Head and Neck Cancer Pipeline Analysis for a closer look at promising breakthroughs @ HPV+ Recurrent/Metastatic Head and Neck Cancer Clinical Trials and Studies

HPV+ Recurrent/Metastatic Head and Neck Cancer Emerging Drugs

  • CUE 101: Cue Biopharma

Cue Biopharma is advancing a pipeline of targeted interleukin 2 (IL-2)-based immunotherapies for multiple types of cancers with high unmet needs. The CUE-100 series of biologics have the potential to improve efficacy and reduce the severe toxicities associated with non-specific IL-2 cancer immunotherapies. CUE-101, has already demonstrated clinical activity and favorable tolerability as a monotherapy in a Phase 1 trial in patients with human papilloma virus (HPV16+) recurrent/metastatic head and neck squamous cell carcinoma (HNSCC).

  • BNT 113: BioNTech

BNT113 is an mRNA cancer vaccine encoding two oncoproteins, E6 and E7,that are frequently found in HPV16+ solid cancers aiming to trigger a strong and precise immune response in patients with HPV16+ head and neck squamous cell carcinoma (HNSCC). BNT113 is currently being evaluated in a Phase 2 study, AHEAD-MERIT, in combination with Merck’s pembrolizumab, a PD-1 inhibitor, vs. pembrolizumab alone in patients with unresectable recurrent or metastatic HPV+ PD-1+ HNSCCs. Results from an investigator-initiated Phase 1/2 basket trial, HARE-40, in patients with HPV16+ cancers showed that BNT113 treatment induces potent, antigen-specific T cell responses.

The HPV+ Recurrent/Metastatic Head and Neck Cancer pipeline report provides insights into

  • The report provides detailed insights about companies that are developing therapies for the treatment of HPV+ Recurrent/Metastatic Head and Neck Cancer with aggregate therapies developed by each company for the same.
  • It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for HPV+ Recurrent/Metastatic Head and Neck Cancer Treatment.
  • HPV+ Recurrent/Metastatic Head and Neck Cancer Companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
  • HPV+ Recurrent/Metastatic Head and Neck Cancer Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
  • Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the HPV+ Recurrent/Metastatic Head and Neck Cancer market.

Get a detailed analysis of the latest innovations in the HPV+ Recurrent/Metastatic Head and Neck Cancer pipeline. Explore DelveInsight’s expert-driven report today! @ HPV+ Recurrent/Metastatic Head and Neck Cancer Unmet Needs

HPV+ Recurrent/Metastatic Head and Neck Cancer Companies

BioNTech, Cue Biopharma, Hookipa Pharma, and others.

HPV+ Recurrent/Metastatic Head and Neck Cancer pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration.

  • Intra-articular
  • Intraocular
  • Intrathecal
  • Intravenous
  • Ophthalmic
  • Oral
  • Parenteral
  • Subcutaneous
  • Topical
  • Transdermal

HPV+ Recurrent/Metastatic Head and Neck Cancer Products have been categorized under various Molecule types such as

  • Oligonucleotide
  • Peptide
  • Small molecule

Download DelveInsight’s latest report to gain strategic insights into upcoming HPV+ Recurrent/Metastatic Head and Neck Cancer Therapies and key HPV+ Recurrent/Metastatic Head and Neck Cancer Developments @ HPV+ Recurrent/Metastatic Head and Neck Cancer Market Drivers and Barriers, and Future Perspectives

Scope of the HPV+ Recurrent/Metastatic Head and Neck Cancer Pipeline Report

  • Coverage- Global
  • HPV+ Recurrent/Metastatic Head and Neck Cancer Companies- BioNTech, Cue Biopharma, Hookipa Pharma, and others.
  • HPV+ Recurrent/Metastatic Head and Neck Cancer Pipeline Therapies- MEDI0457, Durvalumab, CUE-101, Keytruda, BNT113, Pembrolizumab, palbociclib, Cetuximab, and others.
  • HPV+ Recurrent/Metastatic Head and Neck Cancer Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
  • HPV+ Recurrent/Metastatic Head and Neck Cancer Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III

Which companies are leading the race in HPV+ Recurrent/Metastatic Head and Neck Cancer drug development? Find out in DelveInsight’s exclusive HPV+ Recurrent/Metastatic Head and Neck Cancer Pipeline Report—access it now! @ HPV+ Recurrent/Metastatic Head and Neck Cancer Emerging Drugs and Major Companies

Table of Content

  1. Introduction
  2. Executive Summary
  3. HPV+ Recurrent/Metastatic Head and Neck Cancer: Overview
  4. Pipeline Therapeutics
  5. Therapeutic Assessment
  6. HPV+ Recurrent/Metastatic Head and Neck Cancer– DelveInsight’s Analytical Perspective
  7. Late Stage Products (Pre-Registration)
  8. Drug Name : Company Name
  9. Drug profiles in the detailed report…..
  10. Last Stage Products (Phase III)
  11. Drug Name : Company Name
  12. Drug profiles in the detailed report…..
  13. Mid Stage Products (Phase II)
  14. BNT 113: BioNTech
  15. Drug profiles in the detailed report…..
  16. Preclinical and Discovery Stage Products
  17. Drug Name : Company Name
  18. Drug profiles in the detailed report…..
  19. Inactive Products
  20. HPV+ Recurrent/Metastatic Head and Neck Cancer Key Companies
  21. HPV+ Recurrent/Metastatic Head and Neck Cancer Key Products
  22. HPV+ Recurrent/Metastatic Head and Neck Cancer - Unmet Needs
  23. HPV+ Recurrent/Metastatic Head and Neck Cancer - Market Drivers and Barriers
  24. HPV+ Recurrent/Metastatic Head and Neck Cancer - Future Perspectives and Conclusion
  25. HPV+ Recurrent/Metastatic Head and Neck Cancer Analyst Views
  26. HPV+ Recurrent/Metastatic Head and Neck Cancer Key Companies
  27. Appendix

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