DelveInsight added a report on the “Lamellar ichthyosis Market“. It covers an overview, its causes, signs and symptoms, and therapies. Major players are involved in developing therapies for lamellar ichthyosis. The launch of emerging therapies will significantly impact the lamellar ichthyosis market.
Lamellar ichthyosis Overview
Lamellar Ichthyosis (LI) is a rare genetic disorder, where skin cells are produced at a normal rate, but they do not separate normally at the surface of the outermost layer of skin and are not shed as quickly as they should be which lead to the formation of scale.
Some of the key highlyghts of the lamellar ichthyosis Market Report
- DelveInsight estimate that the total prevalent population of Lamellar Ichthyosis in the 7MM was 4,038 in 2017 for the study period [2017–2030].
- According to our analysts it is estimated that about 2/3rd of the patients suffered from moderate to severe illness.
- Lamellar Ichthyosis was estimated to be around 4.5 in a million; this was the first study to explore the prevalence of inherited Ichthyosis in France.
- Lamellar Ichthyosis companies included such as Timber Pharmaceuticals, Galderma/Mayne Pharma, Krystal Biotech, and others.
- Lamellar Ichthyosis drugs included such as TMB-001, Trifarotene (CD5789), KB105, and others
Get a sample copy of the report @ Lamellar ichthyosis Market Share
Lamellar ichthyosis Symptoms
Infants affected with Lamellar Ichthyosis are born encased in a hyperkeratotic translucent membrane, known as collodion baby, and within 2-week, develop large, thick, brownish lamellar scales with minimal erythema. Additionally, Lamellar Ichthyosis is associated with crumpled ears, alopecia, eclabium, and ectropion.
Lamellar ichthyosis Cause
It is mainly caused by the mutations affecting several different genes, the genes which mainly involved in Lamellar Ichthyosis include TGM1, ABCA12, CYP4F22, NIPAL4 and others like LIPN, ALOX12B. However, most of the cases (~90%) are caused due to mutation in the TGM1 gene.
Lamellar ichthyosis Diagnosis
The diagnosis of Lamellar Ichthyosis is mainly done skin biopsy for histological analysis, electron microscopy, DNA sequencing analysis and immunohistochemical analysis and Ultrasonography.
Lamellar ichthyosis Treatment
There are a very limited options of medications that can be used to treat Ichthyosis. At the present time, there is no cure available to treat Ichthyosis and the current options are only off-label therapies like emollients, keratolytics and retinoids are used for symptomatic treatment. The approach to treatment is largely symptomatic and dictated by clinical signs and symptoms, which vary between patients and within the same individual over time. The main objectives are to maintain barrier function and suppleness and to improve appearance. In the more severe ichthyosis, it is particularly important to acknowledge the unrelenting nature of the condition and to direct affected individuals and their families to groups that offer support.
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Lamellar ichthyosis Epidemiology Segmentation
- Total Prevalent Cases
- Total Diagnosed Prevalent Cases
- Genetic Mutation-specific Cases
- Severity-Specific Diagnosed Prevalent Cases
- Total Treated Cases
Lamellar ichthyosis Emerging Therapies
- KB105
- Trifarotene (CD5789 Cream)
- Isotretinoin (TMB-001)
Lamellar ichthyosis Market Insights
Lamellar Ichthyosis is treated topically with skin barrier repair formulas containing ceramides or cholesterol, moisturizers with petrolatum or lanolin, and mild keratolytics (products containing alpha-hydroxy acids or urea). For infants, providing a moist environment in an isolate and preventing infection are most important. Petrolatum-based creams and ointments are used to keep the skin soft, supple, and hydrated.
Lamellar ichthyosis Market Drivers
- Development of Gene Therapies
- Improvement in the Diagnosis
- Less Competitive Therapeutic Landscape
Lamellar ichthyosis Market Barriers
- Challenges in the Clinical Trials for Therapies
- Misdiagnosis of Lamellar Ichthyosis
- Problems related to Clinical Outcome Measures
- Burden of Disease
Download Sample Report @ Lamellar ichthyosis Market Research Report
Table of content
1. Key Insights
2. Executive Summary of Lamellar Ichthyosis (LI)
3. Competitive Intelligence Analysis for Lamellar Ichthyosis (LI)
4. Lamellar Ichthyosis (LI): Market Overview at a Glance
5. Lamellar Ichthyosis (LI): Disease Background and Overview
6. Patient Journey
7. Lamellar Ichthyosis (LI) Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical Practices
9. Lamellar Ichthyosis (LI) Unmet Needs
10. Key Endpoints of Lamellar Ichthyosis (LI) Treatment
11. Lamellar Ichthyosis (LI) Marketed Products
12. Lamellar Ichthyosis (LI) Emerging Therapies
13. Lamellar Ichthyosis (LI): Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Market Outlook
16. Access and Reimbursement Overview of Lamellar Ichthyosis (LI)
17. KOL Views
18. Market Drivers
19. Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
23. About DelveInsight
About Us
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