Friday, August 29, 2025

T-cell receptor (TCR) Therapy Pipeline 2025: MOA, ROA, FDA-Approved Drugs, and Clinical Trial Progress Assessment by DelveInsight | MediGene AG, Adaptive Biotech, Cell Medica Ltd., Bellicum Pharma

T-cell receptor (TCR) Therapy Pipeline 2025: MOA, ROA, FDA-Approved Drugs, and Clinical Trial Progress Assessment by DelveInsight | MediGene AG, Adaptive Biotech, Cell Medica Ltd., Bellicum Pharma
(Las Vegas, Nevada, United States) As per DelveInsight's assessment, globally, T-cell receptor (TCR) Therapy pipeline constitutes key companies continuously working towards developing T-cell receptor (TCR) Therapy treatment therapies, analysis of Clinical Trials, Therapies, Mechanism of Action, Route of Administration, and Developments analyzes DelveInsight.

 

T-cell receptor (TCR) Therapy Pipeline Insight, 2025" report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the T-cell receptor (TCR) Therapy Market.

 

The T-cell receptor (TCR) Therapy Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.

 

Some of the key takeaways from the T-cell receptor (TCR) Therapy Pipeline Report:

  • Companies across the globe are diligently working toward developing novel T-cell receptor (TCR) Therapy treatment therapies with a considerable amount of success over the years.

  • T-cell receptor (TCR) Therapy companies working in the treatment market are Takara Bio Inc, TCR² Therapeutics, Avada, TScan Therapeutics, Inc., Immatics US, Inc., Takara Bio Inc, T Cells Alaunos Therapeutics, Inc., and others, are developing therapies for the T-cell receptor (TCR) Therapy treatment

  • Emerging T-cell receptor (TCR) Therapy therapies in the different phases of clinical trials are- TBI-2001, TC-520, 800TCR, TSC-100, IMA203, TBI-1301, Autologous, gavo-cel, and others are expected to have a significant impact on the T-cell receptor (TCR) Therapy market in the coming years.

  • In November 2024, Immatics N.V. released an expanded dataset from its ongoing Phase 1b dose expansion study of ACTengine® IMA203 and shared updated Phase 1 dose escalation findings for its next-generation ACTengine® IMA203CD8 TCR-T cell therapy. Furthermore, in November 2024, Affini-T Therapeutics, Inc. presented a Trial-In-Progress poster highlighting its Phase 1 clinical trial of AFNT-211, which targets KRAS G12V, at the 39th Annual Meeting of the Society for Immunotherapy of Cancer (SITC), held in Houston, TX, from November 6–10.

  • In October 2024, Matica Biotechnology, a Texas-based viral vector CDMO, has formed a strategic partnership with Mongoose Bio, a pioneering biotech company. The collaboration aims to support the development and production of lentivirus to advance Mongoose Bio’s TCR-T pipeline for cancer therapies.

  • In October 2024, Cellipont Bioservices and Mongoose Bio have entered into an agreement covering technology transfer, process development, and cGMP manufacturing support for Mongoose Bio’s autologous TCR-T cell therapy candidate, MGB-001.

 

T-cell receptor (TCR) Therapy Overview

Adoptive therapy based on the T-cell receptor (TCR) uses genetically altered cells that are targeted against particular tumor markers. Leukapheresis, the production of transduced TCR product, lymphodepletion, infusion of the TCR-based adoptive treatment, and patient screening (e.g., for HLA-A and specific tumor targets) are all necessary steps in an organized and integrated process for this therapeutic modality.

 

Get a Free Sample PDF Report to know more about T-cell receptor (TCR) Therapy Pipeline Therapeutic Assessment-

https://www.delveinsight.com/report-store/t-cell-therapy-pipeline-insight

 

Emerging T-cell receptor (TCR) Therapy Drugs Under Different Phases of Clinical Development Include:

  • TBI-2001: Takara Bio Inc

  • TC-520: TCR² Therapeutics

  • 800TCR: Avada

  • TSC-100: TScan Therapeutics, Inc.

  • IMA203: Immatics US, Inc.

  • TBI-1301: Takara Bio Inc

  • Autologous: T Cells Alaunos Therapeutics, Inc.

  • gavo-cel: TCR² Therapeutics

 

T-cell receptor (TCR) Therapy Pipeline Therapeutics Assessment

  • T-cell receptor (TCR) Therapy Assessment by Product Type

  • T-cell receptor (TCR) Therapy By Stage and Product Type

  • T-cell receptor (TCR) Therapy Assessment by Route of Administration

  • T-cell receptor (TCR) Therapy By Stage and Route of Administration

  • T-cell receptor (TCR) Therapy Assessment by Molecule Type

  • T-cell receptor (TCR) Therapy by Stage and Molecule Type

 

DelveInsight's T-cell receptor (TCR) Therapy Report covers around products under different phases of clinical development like

  • Late-stage products (Phase III)

  • Mid-stage products (Phase II)

  • Early-stage product (Phase I)

  • Pre-clinical and Discovery stage candidates

  • Discontinued & Inactive candidates

  • Route of Administration

 

Further T-cell receptor (TCR) Therapy product details are provided in the report. Download the T-cell receptor (TCR) Therapy pipeline report to learn more about the emerging T-cell receptor (TCR) Therapy therapies

 

Some of the key companies in the T-cell receptor (TCR) Therapy Therapeutics Market include:

Key companies developing therapies for T-cell receptor (TCR) Therapy are - MediGene AG, Adaptive Biotechnologies, Cell Medica Ltd., Bellicum Pharmaceuticals, Takara Bio, T-Cure, BioNTech, TScan therapeutics, Adaptimmune, TCR2 Therapeutics, Immatics N.V., Anocca AB, Gritstone, LION TCR, Guangzhou FineImmune Biotechnology, Immatics US, Inc., Lonza Walkersville, Inc., PACT Pharma, Inc., Bluebird Bio, T-knife Therapeutics, GlaxoSmithKline, Eureka Therapeutics and others.

 

T-cell receptor (TCR) Therapy Pipeline Analysis:

The T-cell receptor (TCR) Therapy pipeline report provides insights into

  • The report provides detailed insights about companies that are developing therapies for the treatment of T-cell receptor (TCR) Therapy with aggregate therapies developed by each company for the same.

  • It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for T-cell receptor (TCR) Therapy Treatment.

  • T-cell receptor (TCR) Therapy key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.

  • T-cell receptor (TCR) Therapy Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.

  • Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the T-cell receptor (TCR) Therapy market.

The report is built using data and information traced from the researcher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.

 

Download Sample PDF Report to know more about T-cell receptor (TCR) Therapy drugs and therapies

 

T-cell receptor (TCR) Therapy Pipeline Market Drivers

  • Rise in global prevalence Cancer, increasing research and development activities, technological advancements are some of the important factors that are fueling the T-cell receptor (TCR) Therapy Market.

 

T-cell receptor (TCR) Therapy Pipeline Market Barriers

  • However, complexity of the Therapy, inaccessibility for many patients needing immediate therapy, lack of known Tumor Markers and other factors are creating obstacles in the T-cell receptor (TCR) Therapy Market growth.

 

Scope of T-cell receptor (TCR) Therapy Pipeline Drug Insight

  • Coverage: Global

  • Key T-cell receptor (TCR) Therapy Companies: Takara Bio Inc, TCR² Therapeutics, Avada, TScan Therapeutics, Inc., Immatics US, Inc., Takara Bio Inc, T Cells Alaunos Therapeutics, Inc., and others

  • Key T-cell receptor (TCR) Therapy Therapies: TBI-2001, TC-520, 800TCR, TSC-100, IMA203, TBI-1301, Autologous, gavo-cel, and others

  • T-cell receptor (TCR) Therapy Therapeutic Assessment: T-cell receptor (TCR) Therapy current marketed and T-cell receptor (TCR) Therapy emerging therapies

  • T-cell receptor (TCR) Therapy Market Dynamics: T-cell receptor (TCR) Therapy market drivers and T-cell receptor (TCR) Therapy market barriers

 

Request for Sample PDF Report for T-cell receptor (TCR) Therapy Pipeline Assessment and clinical trials

 

Table of Contents

1. T-cell receptor (TCR) Therapy Report Introduction

2. T-cell receptor (TCR) Therapy Executive Summary

3. T-cell receptor (TCR) Therapy Overview

4. T-cell receptor (TCR) Therapy- Analytical Perspective In-depth Commercial Assessment

5. T-cell receptor (TCR) Therapy Pipeline Therapeutics

6. T-cell receptor (TCR) Therapy Late Stage Products (Phase II/III)

7. T-cell receptor (TCR) Therapy Mid Stage Products (Phase II)

8. T-cell receptor (TCR) Therapy Early Stage Products (Phase I)

9. T-cell receptor (TCR) Therapy Preclinical Stage Products

10. T-cell receptor (TCR) Therapy Therapeutics Assessment

11. T-cell receptor (TCR) Therapy Inactive Products

12. Company-University Collaborations (Licensing/Partnering) Analysis

13. T-cell receptor (TCR) Therapy Key Companies

14. T-cell receptor (TCR) Therapy Key Products

15. T-cell receptor (TCR) Therapy Unmet Needs

16 . T-cell receptor (TCR) Therapy Market Drivers and Barriers

17. T-cell receptor (TCR) Therapy Future Perspectives and Conclusion

18. T-cell receptor (TCR) Therapy Analyst Views

19. Appendix

20. About DelveInsight

 

About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.

 

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